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|Trade names||Singulair, others|
|Pregnancy category||AU: B1 US: B (No risk in non-human studies)|
|Routes of administration||By mouth|
|Drug class||Leukotriene receptor antagonist|
|ATC code||R03DC03 ( WHO )|
|Legal status||AU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only|
|Metabolism||Liver (CYP2C8-major, CYP3A4 and CYP2C9-minor) |
|Elimination half-life||2.7–5.5 hours|
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This sometimes happens in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered.ost-marketing ExperienceAdverse reactions reported in post-marketing use are listed, by System Organ Class and specific Adverse Experience Term, in the table below.
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Antihistamine medications can reduce symptoms such as sneezing, itchy eyes, and sinus pressure.o dose adjustment is needed when SINGULAIR is co-administered with theophylline, prednisone, prednisolone, oral contraceptives, terfenadine, digoxin, warfarin, thyroid hormones, sedative hypnotics, non-steroidal anti-inflammatory agents, benzodiazepines, decongestants, and Cytochrome P450 CYP enzyme inducers seeClinical Pharmacology.
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Singulair is used to prevent asthma attacks in adults and children as young as 12 months old.In pediatric patients 6 to 14 singulair fors capsular contracture treatment of age, using the 5-mg chewable tablet, a 2-day crossover study demonstrated effects similar to those observed in adults when exercise challenge was conducted at the end of the dosing interval i. 20 to 24 hours after the preceding dose Daily administration of SINGULAIR for the chronic treatment of asthma has not been established to prevent acute episodes of exercise-induced bronchoconstriction.
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