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Clinical data
Trade namesSingulair, others
Pregnancy categoryAU: B1 US: B (No risk in non-human studies)
Routes of administrationBy mouth
Drug classLeukotriene receptor antagonist
ATC codeR03DC03 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Protein binding99%
MetabolismLiver (CYP2C8-major, CYP3A4 and CYP2C9-minor) [1]
Elimination half-life2.7–5.5 hours

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Baserat p in vitro effects, f rv ntas inte kliniskt viktiga l kemedelsinteraktioner med mindre potenta h mmare av CYP 2C8 t ex trimetoprim Co-administrering av montelukast med itrakonasol, en financial h mmare av CYP 3A4, gav ingen signifikant kning av den systemiska exponeringen av montelukast.

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If you're using a metered dose inhaler, use a spacer and rinse your mouth with water after each use to reduce the amount of drug remaining in your mouth. These singulair fors capsular contracture treatment block the effects of leukotrienes, immune system chemicals that cause asthma symptoms.Tell your healthcare provider right away if you or your singulair for capsular contracture treatment have any of these symptoms while taking SINGULAIR: Increase in certain white blood cells eosinophils and possible inflamed blood vessels throughout the body systemic vasculitis Rarely, this can happen in people with asthma who take SINGULAIR.

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Antihistamine medications can reduce symptoms such as sneezing, itchy eyes, and sinus pressure.o dose adjustment is needed when SINGULAIR is co-administered with theophylline, prednisone, prednisolone, oral contraceptives, terfenadine, digoxin, warfarin, thyroid hormones, sedative hypnotics, non-steroidal anti-inflammatory agents, benzodiazepines, decongestants, and Cytochrome P450 CYP enzyme inducers seeClinical Pharmacology.

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Singulair is used to prevent asthma attacks in adults and children as young as 12 months old.In pediatric patients 6 to 14 singulair fors capsular contracture treatment of age, using the 5-mg chewable tablet, a 2-day crossover study demonstrated effects similar to those observed in adults when exercise challenge was conducted at the end of the dosing interval i. 20 to 24 hours after the preceding dose Daily administration of SINGULAIR for the chronic treatment of asthma has not been established to prevent acute episodes of exercise-induced bronchoconstriction.

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